Curcumin supplementation is shown to halt the progression of diabetes in pre-diabetics

The trials showed that two DPP-4 inhibitors — alogliptin (Nesina) and saxagliptin (Onglyza) — did not have any positive or negative effects on cardiovascular events. There was, however, an increased risk of heart failure hospitalization with saxagliptin. Running concurrently with that session will be one focusing on the intersection of heart failure and diabetes, and how best to manage patients with both conditions. Several sessions throughout the meeting will deal with cardiovascular issues, including a debate on how useful albuminuria is for predicting cardiovascular risk, a review on lipid-lowering in the setting of diabetes, and multiple oral abstract presentations with original research.
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Brown Researchers Show Protein Key To Predicting Diabetes

Specifically, 80 percent of patients who had the surgeries met target blood sugar levels of 7 percent HbA1c, a level recommended by the American Diabetes Association . Nearly 30 percent of those who underwent a gastric bypass procedure experienced complete remission of diabetes that allowed them to stay off medication for at least five years, effectively curing them. “That was a remarkable finding,” Dr. Stacy Brethauer, the study’s author and an associate director of the Cleveland Clinic’s Bariatric & Metabolic Institute, said to CBSNews.com.
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Study: Weight loss surgery keeps diabetes at bay long term, reverses complications

Additionally, the researchers determined that the supplemented group had significantly improved pancreatic beta cell function (beta cells release insulin to control serum blood glucose levels) and decreased levels of insulin resistance. The study authors concluded “Our study showed that the curcumin extract can effectively prevent the prediabetes population from developing type 2 diabetes mellitus… because of its benefits and safety, we propose that curcumin extract may be used for an intervention therapy for the prediabetes population.” This study used a daily regimen of 730 mg of a standardized curcumin extract to achieve the results reported. Most health-minded adults will want to supplement with 500 to 1,000 mg of curcumin each day to prevent the damaging health effects of metabolic syndrome and diabetes. Sources for this article include: http://www.lef.org About the author: John Phillip is a Certified Nutritional Consultant and Health Researcher and Author who writes regularly on the cutting edge use of diet, lifestyle modifications and targeted supplementation to enhance and improve the quality and length of life. John is the author of ‘Your Healthy Weight Loss Plan’, a comprehensive EBook explaining how to use Diet, Exercise, Mind and Targeted Supplementation to achieve your weight loss goal.
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Knowing that these factors are linked to the biomarker suggests that experiments could be done to see whether changing those factors exercising more, for example could change levels of the protein over time in individuals, Liu said. That, in turn, could affect their ultimate diabetes risk. In addition, the findings may also help explain the possible physiological connections between those factors and risk of type 2 diabetes. For example, drinking regular coffee and having a lower BMI have each independently been associated with a lower risk for the condition. The new research suggests that SHBG may have an intermediating role in those associations.
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